Safety data sheet for Chloroform
CAS 67-66-3
This is the free preview of a draft SDS for Chloroform — Sections 1, 2 and 9, generated from the sources named below. The full 16-section draft, with your own company in Section 1, is $5 per document.
Typically documented by: Laboratory solvent, extraction.
Draft safety data sheet — preview
Sections 1, 2, 9 of 16
- CAS number
- 67-66-3
- Molecular formula
- CHCl3
- Molecular weight
- 119.37 g/mol
- Signal word
- Danger
Hazard classification
- GHS06 — Acute toxicity
- GHS08 — Serious health hazard
- GHS07 — Health hazard — irritant
- GHS09 — Hazardous to the environment
- H302: Harmful if swallowed.
- H315: Causes skin irritation.
- H319: Causes serious eye irritation.
- H331: Toxic if inhaled.
- H351: Suspected of causing cancer.
- H361d: Suspected of damaging the unborn child.
- H372: Causes damage to organs through prolonged or repeated exposure.
- H401: Toxic to aquatic life.
Section 1 — Identification
1.1 Product identifier
Product identifier: Chloroform
Chemical name (IUPAC): chloroform
CAS number: 67-66-3
PubChem CID reference: 6212
Synonyms: CHLOROFORM; Trichloromethane; Trichlormethan; Trichloroform; Formyl trichloride; Methane, trichloro-; Methenyl trichloride; Methyl trichloride; Methane trichloride; Chloroforme
1.2 Relevant identified uses of the substance or mixture and uses advised against
Relevant identified uses: Laboratory reagent, industrial processing aid, formulation component, and internal product-stewardship review subject to supplier confirmation.
Uses advised against: Consumer, medical, food, or any other use not covered by the supplier's label, technical instructions, or exposure scenario.
Section 2 — Hazards Identification
2.1 Classification of the substance or mixture
Classification basis: OSHA 29 CFR 1910.1200 Appendix A, aligned to the GHS Rev. 7 hazard classes.
Classification: Acute Toxicity, Category 4 — Oral (Acute Tox. 4 (Oral)) [H302]
Classification: Skin Irritation, Category 2 (Skin Irrit. 2) [H315]
Classification: Eye Irritation, Category 2 (Eye Irrit. 2) [H319]
Classification: Acute Toxicity, Category 3 — Inhalation (Acute Tox. 3 (Inhalation)) [H331]
Classification: Carcinogenicity, Category 2 (Carc. 2) [H351]
Classification: Specific Target Organ Toxicity, Repeated Exposure, Category 1 (STOT RE 1) [H372]
Classification: Hazardous to the Aquatic Environment, Acute Hazard, Category 2 (Aquatic Acute 2) [H401]
2.2 Label elements
Signal word: Danger
GHS pictograms: GHS06 (Toxic), GHS08 (Health Hazard), GHS07 (Exclamation), GHS09 (Environmental Hazard)
Hazard statement: H302: Harmful if swallowed.
Hazard statement: H315: Causes skin irritation.
Hazard statement: H319: Causes serious eye irritation.
Hazard statement: H331: Toxic if inhaled.
Hazard statement: H351: Suspected of causing cancer.
Hazard statement: H361d: Suspected of damaging the unborn child.
Hazard statement: H372: Causes damage to organs through prolonged or repeated exposure.
Hazard statement: H401: Toxic to aquatic life.
Precautionary statement: P203: Obtain, read and follow all safety instructions before use.
Precautionary statement: P260: Do not breathe dust/fume/gas/mist/vapors/spray.
Precautionary statement: P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
Precautionary statement: P264: Wash hands thoroughly after handling.
Precautionary statement: P270: Do not eat, drink or smoke when using this product.
Precautionary statement: P271: Use only outdoors or in a well-ventilated area.
Precautionary statement: P273: Avoid release to the environment.
Precautionary statement: P280: Wear protective gloves, protective clothing, eye protection, face protection, and hearing protection.
Precautionary statement: P301+P317: IF SWALLOWED: Get medical help.
Precautionary statement: P302+P352: IF ON SKIN: Wash with plenty of water.
Precautionary statement: P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
Precautionary statement: P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
Precautionary statement: P316: Get emergency medical help immediately.
Precautionary statement: P318: if exposed or concerned, get medical advice.
Precautionary statement: P319: Get medical help if you feel unwell.
Precautionary statement: P330: Rinse mouth.
Precautionary statement: P332+P317: If skin irritation occurs: Get medical help.
Precautionary statement: P337+P317: If eye irritation persists: Get medical help.
Precautionary statement: P362+P364: Take off contaminated clothing and wash it before reuse.
Precautionary statement: P403+P233: Store in a well-ventilated place. Keep container tightly closed.
Precautionary statement: P405: Store locked up.
Precautionary statement: P501: Dispose of contents/container in accordance with local, regional, national, and international regulations.
Section 9 — Physical and Chemical Properties
9.1 Information on basic physical and chemical properties
Physical form: Liquid
Appearance: Highly refractive, nonflammable, heavy, very liquid
Odor: Pleasant, etheric, nonirritating
Boiling point: 62°C (144°F) at 1013 hPa
Melting point: -63.5°C (-82°F)
Flash point: Not available
Density: 1.4788 g/cm³ at 25°C
Vapor pressure: 263 hPa at 25°C
Water solubility: Slightly soluble (8 g/L at 20°C; Sigma-Aldrich SDS / PubChem ICSC reference)
Log Pow (log Kow): 1.97
Vapor density: 4.12 (air = 1)
Lower explosive limit: Not available
Upper explosive limit: Not available
Auto-ignition temperature: Not available
Viscosity: 5.63 millipoises at 20 °C; 5.10 millipoises at 30 °C
pH: Not available
9.2 Other information
Other information: Additional classification-supporting physical hazard data should be confirmed from the customer-specific product specification where required.
Sources
- ECHA C&L Inventory — harmonised CLP entry
- PubChem — GHS classification
- PubChem — compound record
- PubChem — names and identifiers
- PubChem — regulatory information
- PubChem — toxicity data
- PubChem — transport information
Sections 1.3 and 1.4 are withheld here because the supplier and emergency contact blocks carry your own company details in the draft you buy. Every draft needs review by a competent person before it is issued.
Measured values for Chloroform, and where each one comes from
33 measured values for 10 properties, read from 4 public databases. On 4 properties the records differ. Each reading is shown with its own record. Follow any record to read the value at its source.
Boiling point
4 records, 61 to 62 °C
Used with vapour pressure to judge how readily the substance reaches the air you breathe.
- 143 °F
- NIOSH Pocket Guide
- 61.17 °C @760 [mm Hg]
- PAC Chemical Database, U.S. Department of Energy
Melting point
4 records agree
Fixes the physical state at handling temperature, which the label and the transport class depend on.
- -82 °F
- NIOSH Pocket Guide
Vapour pressure
5 records differ
The higher it is, the faster the substance evaporates into the workplace air at room temperature.
- VP: 100 mm Hg at 10.4 °C
- Hazardous Substances Data Bank (HSDB)
- 197 mm Hg at 25 °C
- Hazardous Substances Data Bank (HSDB)
- 160 mmHg
- NIOSH Pocket Guide
- 75 [mm Hg] @4.3 °C
- PAC Chemical Database, U.S. Department of Energy
Vapour density
2 records differ
Above 1 the vapour sinks and collects in pits, sumps and low enclosed spaces.
- 4.12 (Air = 1)
- Hazardous Substances Data Bank (HSDB)
Density
5 records differ
Needed to convert between mass and volume on the label, in transport papers and in a spill estimate.
- 1.4788 g/cu cm at 25 °C
- Hazardous Substances Data Bank (HSDB)
- Density: 1.484 at 20 °C/20 °C
- Hazardous Substances Data Bank (HSDB)
- 1.4788 @25 °C
- PAC Chemical Database, U.S. Department of Energy
Solubility
6 records, each a different case
Determines spill behaviour, the right extinguishing media and the correct first-aid rinse.
- In water, 7.95X10+3 mg/L at 25 °C
- Hazardous Substances Data Bank (HSDB)
- Highly soluble in water
- Hazardous Substances Data Bank (HSDB)
- One mL dissolves in about 200 mL water at 25 °C
- Hazardous Substances Data Bank (HSDB)
- Miscible with alcohol, benzene, ether, petroleum ether, carbon tetrachloride, carbon disulfide, oils
- Hazardous Substances Data Bank (HSDB)
- For more Solubility (Complete) data for Chloroform (6 total), please visit the HSDB record page
- Hazardous Substances Data Bank (HSDB)
- (77 °F): 0.5%
- NIOSH Pocket Guide
Partition coefficient (log Kow)
1 record
Indicates whether the substance accumulates in fat or in water, which drives the environmental sections.
- log Kow = 1.97
- Hazardous Substances Data Bank (HSDB)
Viscosity
1 record
Governs how far a spill spreads and how fast it soaks into a surface or a sorbent.
- 5.63 millipoises at 20 °C; 5.10 millipoises at 30 °C
- Hazardous Substances Data Bank (HSDB)
Odour
4 records, each a different case
Odour is a warning property only. Many substances are hazardous well below the concentration you can smell.
- Pleasant, etheric, nonirritating
- Hazardous Substances Data Bank (HSDB)
- Pleasant odor
- Hazardous Substances Data Bank (HSDB)
- Odor threshold: 205-307 ppm
- Hazardous Substances Data Bank (HSDB)
- Characteristic odor
- Hazardous Substances Data Bank (HSDB)
Decomposition temperature
1 record
The temperature at which the substance breaks down, often into products more hazardous than itself.
- On prolonged heating with water at 225 °C, decomp to formic acid, carbon monoxide, and hydrogen chloride occurs
- Hazardous Substances Data Bank (HSDB)
These are the public records read for Chloroform, published here unchanged. Where two records disagree, the draft you buy states the value and names the record behind it, so a reviewer can see what was chosen. Every draft needs review by a competent person before it is issued.
Get the full draft SDS for Chloroform
The draft covers all 16 sections under OSHA 29 CFR 1910.1200 and GHS Rev. 7, or the CLP EC 1272/2008 layout for the EU. Each draft arrives as an editable .docx and a PDF with an appendix naming the source of each value, in about 60 seconds. $5 per document, no account.